Cisplatin

Pt(NH₃)₂Cl₂

IUPAC: cis-Diamminedichloroplatinum(II)

CAS: 15663-27-1

Übersicht

Cisplatin is one of the most effective anticancer drugs, used to treat testicular, ovarian, bladder, and many other cancers. It crosslinks DNA to kill cancer cells.

Zusammensetzung

Element Symbol Atome Atommasse
Hydrogen H 6 1,0080
Nitrogen N 2 14,0070
Chlorine Cl 2 35,4500
Platinum Pt 1 195,0800

Elementare Zusammensetzung

H
Hydrogen ×6
2,0%
N
Nitrogen ×2
9,3%
Cl
Chlorine ×2
23,6%
Pt
Platinum ×1
65,0%

Verwendung

  • • Cancer chemotherapy
  • • Testicular cancer
  • • Ovarian cancer
  • • Bladder cancer

Wissenswertes

  • ✦ Cured Lance Armstrong's testicular cancer; cure rate for testicular cancer is now over 95% with cisplatin

Sicherheit

  • ⚠ Kidney toxicity
  • ⚠ Nausea
  • ⚠ Hearing loss
  • ⚠ Nerve damage

Structure

SMILES

N.N.Cl[Pt]Cl

Eigenschaften

Typ
inorganic
Zustand
solid
Molmasse
300,05 g/mol
Dichte
3,7400 g/cm³
Schmelzpunkt
270,0 °C
Löslichkeit
2.5 g/L at 25°C

Molecular Descriptors

Exact Mass
298,9556
TPSA
2,0 Ų
H-Bond Donors
2
H-Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
5
Complexity
7,0

Verwandte Verbindungen

Diborane

B₂H₆

Arsine

AsH₃

Boron Trichloride

BCl₃

Gallium Arsenide

GaAs

Barium Ferrite

BaFe₁₂O₁₉

Barium Titanate

BaTiO₃

Calcium Aluminate Cement

CaO·Al₂O₃

Nitrogen Trifluoride

NF₃

Aluminum Nitride

AlN

Aluminum Chloride

AlCl₃

Frequently Asked Questions

What is Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is a inorganic compound with the IUPAC name cis-Diamminedichloroplatinum(II).
What is the molecular weight of Cisplatin?
Cisplatin has a molar mass of 300.05 g/mol.
What state is Cisplatin at room temperature?
Cisplatin is a solid at room temperature.
Is Cisplatin organic or inorganic?
Cisplatin is classified as an inorganic compound.
What elements make up Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is composed of Hydrogen (H), Nitrogen (N), Chlorine (Cl), Platinum (Pt).