Cisplatin

Pt(NH₃)₂Cl₂

IUPAC: cis-Diamminedichloroplatinum(II)

CAS: 15663-27-1

Ikhtisar

Cisplatin is one of the most effective anticancer drugs, used to treat testicular, ovarian, bladder, and many other cancers. It crosslinks DNA to kill cancer cells.

Komposisi

Unsur Simbol Atom Massa Atom
Hydrogen H 6 1,0080
Nitrogen N 2 14,0070
Chlorine Cl 2 35,4500
Platinum Pt 1 195,0800

Komposisi Elemental

H
Hydrogen ×6
2,0%
N
Nitrogen ×2
9,3%
Cl
Chlorine ×2
23,6%
Pt
Platinum ×1
65,0%

Kegunaan

  • • Cancer chemotherapy
  • • Testicular cancer
  • • Ovarian cancer
  • • Bladder cancer

Fakta Menarik

  • ✦ Cured Lance Armstrong's testicular cancer; cure rate for testicular cancer is now over 95% with cisplatin

Keselamatan

  • ⚠ Kidney toxicity
  • ⚠ Nausea
  • ⚠ Hearing loss
  • ⚠ Nerve damage

Structure

SMILES

N.N.Cl[Pt]Cl

Sifat

Jenis
inorganic
Keadaan
solid
Massa Molar
300,05 g/mol
Kerapatan
3,7400 g/cm³
Titik Lebur
270,0 °C
Kelarutan
2.5 g/L at 25°C

Molecular Descriptors

Exact Mass
298,9556
TPSA
2,0 Ų
H-Bond Donors
2
H-Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
5
Complexity
7,0

Senyawa Terkait

Arsine

AsH₃

Barium Ferrite

BaFe₁₂O₁₉

Calcium Aluminate Cement

CaO·Al₂O₃

Aluminum Nitride

AlN

Ammonium Persulfate

(NH₄)₂S₂O₈

Calcium Hydride

CaH₂

Xenon Difluoride

XeF₂

Magnesium Silicate

Mg₃Si₄O₁₀(OH)₂

Hydroxylamine

NH₃O

Diborane

B₂H₆

Frequently Asked Questions

What is Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is a inorganic compound with the IUPAC name cis-Diamminedichloroplatinum(II).
What is the molecular weight of Cisplatin?
Cisplatin has a molar mass of 300.05 g/mol.
What state is Cisplatin at room temperature?
Cisplatin is a solid at room temperature.
Is Cisplatin organic or inorganic?
Cisplatin is classified as an inorganic compound.
What elements make up Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is composed of Hydrogen (H), Nitrogen (N), Chlorine (Cl), Platinum (Pt).