Penicillin G

C₁₆H₁₈N₂O₄S

IUPAC: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 61-33-6

ภาพรวม

Penicillin G was the first antibiotic discovered, by Alexander Fleming in 1928 from the mold Penicillium notatum. It works by inhibiting bacterial cell wall synthesis. Its discovery revolutionized medicine and has saved an estimated 200 million lives.

องค์ประกอบ

ธาตุ	สัญลักษณ์	อะตอม	มวลอะตอม
Hydrogen	H	18	1.0080
Carbon	C	16	12.0110
Nitrogen	N	2	14.0070
Oxygen	O	4	15.9990
Sulfur	S	1	32.0600

องค์ประกอบพื้นฐาน

Hydrogen ×18

5.4%

Carbon ×16

57.5%

Nitrogen ×2

8.4%

Oxygen ×4

19.1%

Sulfur ×1

9.6%

การใช้งาน

• Antibiotic for bacterial infections
• Syphilis treatment
• Streptococcal infection treatment
• Starting material for semi-synthetic penicillins

ข้อเท็จจริงที่น่าสนใจ

✦ Fleming noticed mold contamination on a Petri dish had killed surrounding bacteria, leading to penicillin's discovery
✦ Mass production of penicillin saved countless lives during World War II

ความปลอดภัย

⚠ Allergic reactions (up to 10% of population)
⚠ Anaphylaxis in severe cases
⚠ Antibiotic resistance

Structure

SMILES

CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C

คุณสมบัติ

ประเภท: organic
สถานะ: solid
มวลโมลาร์: 334.39 g/mol
ความหนาแน่น: 1.4100 g/cm³
จุดหลอมเหลว: 214.0 °C
การละลาย: soluble

Molecular Descriptors

Exact Mass: 334.0987
XLogP: 1.8
TPSA: 112.0 Å²
H-Bond Donors: 2
H-Bond Acceptors: 5
Rotatable Bonds: 4
Heavy Atoms: 23
Complexity: 530.0

หรือเรียกอีกชื่อว่า

Benzylpenicillin Penicillin

สารประกอบที่เกี่ยวข้อง

Caffeine

C₈H₁₀N₄O₂

Coumarin

C₉H₆O₂

Acetone

(CH₃)₂CO

Acrylic Acid

C₃H₄O₂

Cysteine

C₃H₇NO₂S

DDT

C₁₄H₉Cl₅

Alanine

C₃H₇NO₂

Diazepam

C₁₆H₁₃ClN₂O

Dichloromethane

CH₂Cl₂

Butane

C₄H₁₀

Frequently Asked Questions

What is Penicillin G?

Penicillin G (C₁₆H₁₈N₂O₄S) is a organic compound with the IUPAC name (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

What is the molecular weight of Penicillin G?

Penicillin G has a molar mass of 334.39 g/mol.

What state is Penicillin G at room temperature?

Penicillin G is a solid at room temperature.

Is Penicillin G organic or inorganic?

Penicillin G is classified as an organic compound.

What elements make up Penicillin G?

Penicillin G (C₁₆H₁₈N₂O₄S) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O), Sulfur (S).