एथिल एसीटेट का फिशर एस्टरीकरण

फलों की सुगंध वाले एस्टर का संश्लेषण

Organic Synthesis Advanced (University) 90 मिनट ~$20.00

उद्देश्य

सल्फ्यूरिक अम्ल उत्प्रेरित, एसिटिक अम्ल और इथेनॉल के फिशर एस्टरीकरण द्वारा एथिल एसीटेट (नेल पॉलिश रिमूवर की सुगंध) का संश्लेषण करें।

पृष्ठभूमि

Fischer esterification is the acid-catalyzed condensation of a carboxylic acid with an alcohol to form an ester and water. The reaction is reversible, and excess alcohol is used to drive the equilibrium toward product formation. Ethyl acetate has a characteristic sweet, fruity smell and is widely used as an industrial solvent.

सुरक्षा चेतावनियाँ

Concentrated sulfuric acid is extremely corrosive
Glacial acetic acid causes burns
Ethanol and ethyl acetate are flammable — no open flames
Work in a fume hood
Add sulfuric acid slowly to the mixture

आवश्यक PPE

goggles gloves lab_coat

सामग्री

Glacial acetic acid (10 mL)
Corrosive
Ethanol (absolute) (15 mL)
Excess to drive equilibrium
Sulfuric acid (H₂SO₄) (2 mL)
Concentrated, catalyst
Sodium bicarbonate solution (50 mL)
5% for washing
Anhydrous sodium sulfate (5 g)
Drying agent

उपकरण

Round-bottom flask (100 mL) Reflux condenser Heating mantle Separating funnel Boiling chips Thermometer

प्रक्रिया

Add 15 mL ethanol and 10 mL glacial acetic acid to the round-bottom flask with boiling chips.

3 मिनट Handle acetic acid in fume hood

Slowly add 2 mL concentrated H₂SO₄ as catalyst. Swirl gently to mix.

3 मिनट Add acid slowly — exothermic

Attach the reflux condenser and heat gently at reflux for 45 minutes.

45 मिनट Ensure water is flowing through condenser

Cool the flask. Pour the contents into a separating funnel with 30 mL water.

5 मिनट

Wash the organic layer with 25 mL of 5% NaHCO₃ to remove excess acid. Vent the funnel frequently.

5 मिनट CO₂ gas released — vent carefully

Separate the organic layer (top) and dry over anhydrous Na₂SO₄ for 10 minutes.

12 मिनट

Filter off the drying agent. Carefully smell the product by wafting — note the fruity aroma of ethyl acetate.

3 मिनट Never sniff directly — waft vapors toward nose

Calculate the yield based on the volume collected and the theoretical yield.

5 मिनट

अपेक्षित परिणाम

A clear, colorless liquid with a sweet, fruity smell characteristic of ethyl acetate. Typical yield is 60-70% due to the equilibrium nature of the reaction.

सफाई

Dispose of organic waste in the designated container. Neutralize acid waste before disposal. Rinse all glassware with acetone then water.

विवरण

श्रेणी: Organic Synthesis
कठिनाई: Advanced (University)
अवधि: 90 मिनट
अनुमानित लागत: $20.00
चरण: 8
सामग्री: 5

अधिक प्रयोग

एल्डोल संघनन (डाइबेंजेलएसीटोन) 75 min एसिटामिनोफेन (पेरासिटामोल) की तैयारी 80 min एस्पिरिन (एसिटाइलसैलिसिलिक अम्ल) का संश्लेषण 90 min केला तेल (आइसोएमाइल एसीटेट) संश्लेषण 90 min चाय से कैफीन का निष्कर्षण 90 min नायलॉन 6,10 बनाना (नायलॉन रस्सी ट्रिक) 30 min ल्यूमिनॉल का संश्लेषण 120 min वनस्पति तेल से बायोडीजल उत्पादन 60 min साबुनीकरण द्वारा साबुन बनाना 60 min स्लाइम संश्लेषण (क्रॉस-लिंक्ड PVA) 20 min

Frequently Asked Questions

What is the objective of एथिल एसीटेट का फिशर एस्टरीकरण?

How difficult is एथिल एसीटेट का फिशर एस्टरीकरण?

This experiment is rated as Advanced (University). It takes approximately 90 minutes to complete.

What safety precautions are needed for एथिल एसीटेट का फिशर एस्टरीकरण?

Key safety precautions include: Concentrated sulfuric acid is extremely corrosive; Glacial acetic acid causes burns; Ethanol and ethyl acetate are flammable — no open flames.

What materials are needed for एथिल एसीटेट का फिशर एस्टरीकरण?

The main materials required are: Glacial acetic acid, Ethanol (absolute), Sulfuric acid (H₂SO₄), Sodium bicarbonate solution, Anhydrous sodium sulfate.

What results should I expect from एथिल एसीटेट का फिशर एस्टरीकरण?