Coenzyme A

C₂₁H₃₆N₇O₁₆P₃S

IUPAC: Coenzyme A

CAS: 85-61-0

Overview

Coenzyme A (CoA) is a coenzyme essential for synthesis and oxidation of fatty acids, and the citric acid cycle. Acetyl-CoA is the central molecule of metabolism.

Composition

Element	Symbol	Atoms	Atomic Mass
Hydrogen	H	36	1.0080
Carbon	C	21	12.0110
Nitrogen	N	7	14.0070
Oxygen	O	16	15.9990
Phosphorus	P	3	30.9740
Sulfur	S	1	32.0600

Elemental Composition

Hydrogen ×36

4.7%

Carbon ×21

32.9%

Nitrogen ×7

12.8%

Oxygen ×16

33.4%

Phosphorus ×3

12.1%

Sulfur ×1

4.2%

Uses

• Biochemical research
• Enzyme cofactor

Fun Facts

✦ Acetyl-CoA sits at the crossroads of fat, carbohydrate, and protein metabolism

Structure

SMILES

CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O

Properties

Type: organic
State: solid
Molar Mass: 767.53 g/mol
Solubility: soluble

Molecular Descriptors

Exact Mass: 767.1152
XLogP: -5.8
TPSA: 348.0 Å²
H-Bond Donors: 10
H-Bond Acceptors: 21
Rotatable Bonds: 18
Heavy Atoms: 48
Complexity: 1270.0

Related Compounds

1,2-Dichloroethane

C₂H₄Cl₂

1,3-Butadiene

C₄H₆

1,4-Dioxane

C₄H₈O₂

1-Butanol

C₄H₁₀O

2-Propanol

C₃H₈O

Acetaldehyde

CH₃CHO

Acetamide

C₂H₅NO

Acetic Anhydride

C₄H₆O₃

Acetone

(CH₃)₂CO

Acetonitrile

C₂H₃N

Frequently Asked Questions

What is Coenzyme A?

Coenzyme A (C₂₁H₃₆N₇O₁₆P₃S) is a organic compound with the IUPAC name Coenzyme A.

What is the molecular weight of Coenzyme A?

Coenzyme A has a molar mass of 767.53 g/mol.

What state is Coenzyme A at room temperature?

Coenzyme A is a solid at room temperature.

Is Coenzyme A organic or inorganic?

Coenzyme A is classified as an organic compound.

What elements make up Coenzyme A?

Coenzyme A (C₂₁H₃₆N₇O₁₆P₃S) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O), Phosphorus (P), Sulfur (S).