Nitroglycerin
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Cite "Nitroglycerin"
Nitroglycerin. (n.d.). In Compound. Retrieved from /compound/nitroglycerin/
"Nitroglycerin." Compound, /compound/nitroglycerin/.
@misc{nitroglycerin, title={Nitroglycerin}, url={/compound/nitroglycerin/}}
IUPAC: Propane-1,2,3-triyl trinitrate
CAS: 55-63-0
Overview
Nitroglycerin is a powerful explosive liquid that is also a vasodilator medication for angina (chest pain). Alfred Nobel made it safer by absorbing it in diatomaceous earth to create dynamite. The Nobel Prizes are funded by profits from Nobel's dynamite fortune.
Composition
Uses
- • Dynamite ingredient (absorbed in diatomite)
- • Angina medication (sublingual tablets)
- • Heart failure treatment
- • Mining explosive (in dynamite)
Fun Facts
- ✦ Alfred Nobel was ironically prescribed nitroglycerin for his heart condition
- ✦ Nobel Prize money comes from dynamite profits
Safety
- ⚠ Extremely sensitive to shock, heat, and friction
- ⚠ Can explode from minor disturbance
- ⚠ Causes severe headache from skin absorption
Structure
SMILES
C(C(CO[N+](=O)[O-])O[N+](=O)[O-])O[N+](=O)[O-]
Properties
- Type
- organic
- State
- liquid
- Molar Mass
- 227.09 g/mol
- Density
- 1.5930 g/cm³
- Melting Point
- 13.0 °C
- Boiling Point
- 50.0 °C
- Solubility
- 1.8 g/L at 20°C
Molecular Descriptors
- Exact Mass
- 227.0026
- XLogP
- 1.6
- TPSA
- 165.0 Ų
- H-Bond Donors
- 0
- H-Bond Acceptors
- 9
- Rotatable Bonds
- 5
- Heavy Atoms
- 15
- Complexity
- 218.0