Oxidation of Primary Alcohol to Aldehyde

RCH₂OH + [O] → RCHO + H₂O

Visão geral

Primary alcohols are oxidized to aldehydes using mild oxidizing agents like PCC or Dess-Martin periodinane. Stronger oxidants (KMnO₄, CrO₃) would over-oxidize to the carboxylic acid. The carbon oxidation state changes from -1 to +1. Distilling the aldehyde product during reaction prevents over-oxidation.

Participantes

Papel	Substância	Coeficiente	Estado
Produto	Water H₂O	1	(l)

Exemplo do cotidiano

The formation of acetaldehyde from ethanol in the liver is this type of oxidation, responsible for hangover symptoms.

Importância industrial

A oxidação seletiva de álcoois a aldeídos é fundamental na produção de perfumes e aromas e na síntese de intermediários farmacêuticos.

Propriedades

Tipo: Organic
Reversível: Não
Energia: Exotérmico
ΔH: -175,0 kJ/mol
Catalisador: PCC (pyridinium chlorochromate)

Reações relacionadas

Epoxidation of Alkenes (mCPBA) Swern Oxidation Oxidation of Secondary Alcohol to Ketone E2 Elimination (Dehydrohalogenation) Claisen Condensation (Ethyl Acetate) Aldol Condensation of Acetaldehyde Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Dehydration of Ethanol

Frequently Asked Questions

What is the equation for Oxidation of Primary Alcohol to Aldehyde?

The balanced equation is: RCH₂OH + [O] → RCHO + H₂O.

What type of reaction is Oxidation of Primary Alcohol to Aldehyde?

Oxidation of Primary Alcohol to Aldehyde is a organic reaction.

Is Oxidation of Primary Alcohol to Aldehyde exothermic or endothermic?

Oxidation of Primary Alcohol to Aldehyde is exothermic (releases energy). The enthalpy change (ΔH) is -175.0 kJ/mol.

What conditions are needed for Oxidation of Primary Alcohol to Aldehyde?

This reaction requires a catalyst (PCC (pyridinium chlorochromate)).