Oxidation of Secondary Alcohol to Ketone
R2CHOH + [O] → R2CO + H2O
Overview
Secondary alcohols are oxidized to ketones by various oxidizing agents. Unlike primary alcohols, secondary alcohols cannot be over-oxidized because ketones lack the C-H bond needed for further oxidation. The Jones reagent (CrO₃/H₂SO₄) is a standard reagent for this transformation.
Participants
| Role | Substance | Coefficient | State |
|---|---|---|---|
| Product | Water H₂O | 1 | (l) |
Everyday Example
Acetone (propanone), the simplest ketone and a common nail polish remover solvent, can be made by oxidizing isopropanol.
Industrial Importance
Ketone synthesis is important in pharmaceutical manufacturing, perfume production (muscone, civetone), and in producing industrial solvents.
Properties
- Type
- Organic
- Reversible
- No
- Energy
- Exothermic
- ΔH
- -170.0 kJ/mol
- Catalyst
- CrO₃ in H₂SO₄ (Jones reagent)
Related Reactions
Aldol Condensation of Acetaldehyde
Amide Formation (Acetic Acid + Ammonia)
Baeyer-Villiger Oxidation
Beckmann Rearrangement (Cyclohexanone Oxime)
Bromination of Ethylene
Buchwald-Hartwig Amination
Cannizzaro Reaction of Formaldehyde
Catalytic Hydrogenation of Ethylene
Claisen Condensation (Ethyl Acetate)
Condensation Polymerization (Nylon 6,6)
Frequently Asked Questions
What is the equation for Oxidation of Secondary Alcohol to Ketone?
The balanced equation is: R₂CHOH + [O] → R₂CO + H₂O.
What type of reaction is Oxidation of Secondary Alcohol to Ketone?
Oxidation of Secondary Alcohol to Ketone is a organic reaction.
Is Oxidation of Secondary Alcohol to Ketone exothermic or endothermic?
Oxidation of Secondary Alcohol to Ketone is exothermic (releases energy). The enthalpy change (ΔH) is -170.0 kJ/mol.
What conditions are needed for Oxidation of Secondary Alcohol to Ketone?
This reaction requires a catalyst (CrO₃ in H₂SO₄ (Jones reagent)).