Alpha-Ketoglutaric Acid

C₅H₆O₅

IUPAC: 2-Oxopentanedioic acid

CAS: 328-50-7

Overview

Alpha-ketoglutarate is a key intermediate in the citric acid cycle and plays a central role in amino acid metabolism through transamination reactions.

Composition

Element Symbol Atoms Atomic Mass
Hydrogen H 6 1.0080
Carbon C 5 12.0110
Oxygen O 5 15.9990

Elemental Composition

H
Hydrogen ×6
4.1%
C
Carbon ×5
41.1%
O
Oxygen ×5
54.8%

Uses

  • • Dietary supplement
  • • Biochemical research
  • • Cell culture media

Fun Facts

  • ✦ Links the citric acid cycle to amino acid metabolism through transamination

Structure

SMILES

C(CC(=O)O)C(=O)C(=O)O

Properties

Type
organic
State
solid
Molar Mass
146.10 g/mol
Density
1.4200 g/cm³
Melting Point
115.0 °C
Solubility
very soluble

Molecular Descriptors

Exact Mass
146.0215
XLogP
-0.9
TPSA
91.7 Ų
H-Bond Donors
2
H-Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
10
Complexity
171.0

Related Compounds

1,2-Dichloroethane

C₂H₄Cl₂

1,3-Butadiene

C₄H₆

1,4-Dioxane

C₄H₈O₂

1-Butanol

C₄H₁₀O

2-Propanol

C₃H₈O

Acetaldehyde

CH₃CHO

Acetamide

C₂H₅NO

Acetic Anhydride

C₄H₆O₃

Acetone

(CH₃)₂CO

Acetonitrile

C₂H₃N

Frequently Asked Questions

What is Alpha-Ketoglutaric Acid?
Alpha-Ketoglutaric Acid (C₅H₆O₅) is a organic compound with the IUPAC name 2-Oxopentanedioic acid.
What is the molecular weight of Alpha-Ketoglutaric Acid?
Alpha-Ketoglutaric Acid has a molar mass of 146.1 g/mol.
What state is Alpha-Ketoglutaric Acid at room temperature?
Alpha-Ketoglutaric Acid is a solid at room temperature.
Is Alpha-Ketoglutaric Acid organic or inorganic?
Alpha-Ketoglutaric Acid is classified as an organic compound.
What elements make up Alpha-Ketoglutaric Acid?
Alpha-Ketoglutaric Acid (C₅H₆O₅) is composed of Hydrogen (H), Carbon (C), Oxygen (O).