Atorvastatin

C₃₃H₃₅FN₂O₅

IUPAC: Atorvastatin

CAS: 134523-00-5

Overview

Atorvastatin (Lipitor) was the best-selling pharmaceutical in history, generating over $125 billion in revenue. It lowers cholesterol by inhibiting HMG-CoA reductase.

Composition

Element	Symbol	Atoms	Atomic Mass
Hydrogen	H	35	1.0080
Carbon	C	33	12.0110
Nitrogen	N	2	14.0070
Oxygen	O	5	15.9990
Fluorine	F	1	18.9980

Elemental Composition

Hydrogen ×35

6.3%

Carbon ×33

71.0%

Nitrogen ×2

5.0%

Oxygen ×5

14.3%

Fluorine ×1

3.4%

Uses

• Cholesterol reduction
• Cardiovascular disease prevention

Fun Facts

✦ Lipitor became the first drug to exceed $10 billion in annual sales

Safety

⚠ Muscle pain
⚠ Liver enzyme elevation

Structure

SMILES

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

Properties

Type: organic
State: solid
Molar Mass: 558.64 g/mol
Melting Point: 159.2 °C
Solubility: insoluble

Molecular Descriptors

Exact Mass: 558.2530
XLogP: 5.0
TPSA: 112.0 Å²
H-Bond Donors: 4
H-Bond Acceptors: 6
Rotatable Bonds: 12
Heavy Atoms: 41
Complexity: 822.0

Related Compounds

1,2-Dichloroethane

C₂H₄Cl₂

1,3-Butadiene

C₄H₆

1,4-Dioxane

C₄H₈O₂

1-Butanol

C₄H₁₀O

2-Propanol

C₃H₈O

Acetaldehyde

CH₃CHO

Acetamide

C₂H₅NO

Acetic Anhydride

C₄H₆O₃

Acetone

(CH₃)₂CO

Acetonitrile

C₂H₃N

Frequently Asked Questions

What is Atorvastatin?

Atorvastatin (C₃₃H₃₅FN₂O₅) is a organic compound with the IUPAC name Atorvastatin.

What is the molecular weight of Atorvastatin?

Atorvastatin has a molar mass of 558.64 g/mol.

What state is Atorvastatin at room temperature?

Atorvastatin is a solid at room temperature.

Is Atorvastatin organic or inorganic?

Atorvastatin is classified as an organic compound.

What elements make up Atorvastatin?

Atorvastatin (C₃₃H₃₅FN₂O₅) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O), Fluorine (F).