Proline

C₅H₉NO₂

IUPAC: (2S)-Pyrrolidine-2-carboxylic acid

CAS: 147-85-3

Overview

Proline is unique among the standard amino acids as it has a cyclic side chain bonded to both the nitrogen and alpha carbon. It is crucial for collagen structure.

Composition

Element Symbol Atoms Atomic Mass
Hydrogen H 9 1.0080
Carbon C 5 12.0110
Nitrogen N 1 14.0070
Oxygen O 2 15.9990

Elemental Composition

H
Hydrogen ×9
7.9%
C
Carbon ×5
52.2%
N
Nitrogen ×1
12.2%
O
Oxygen ×2
27.8%

Uses

  • • Pharmaceutical
  • • Food flavor enhancer
  • • Cell culture media

Fun Facts

  • ✦ Makes up about 25% of the amino acids in collagen, enabling its triple helix structure

Structure

SMILES

C1CC(NC1)C(=O)O

Properties

Type
organic
State
solid
Molar Mass
115.13 g/mol
Density
1.3500 g/cm³
Melting Point
228.0 °C
Solubility
very soluble

Molecular Descriptors

Exact Mass
115.0633
XLogP
-2.5
TPSA
49.3 Ų
H-Bond Donors
2
H-Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
8
Complexity
103.0

Related Compounds

1,2-Dichloroethane

C₂H₄Cl₂

1,3-Butadiene

C₄H₆

1,4-Dioxane

C₄H₈O₂

1-Butanol

C₄H₁₀O

2-Propanol

C₃H₈O

Acetaldehyde

CH₃CHO

Acetamide

C₂H₅NO

Acetic Anhydride

C₄H₆O₃

Acetone

(CH₃)₂CO

Acetonitrile

C₂H₃N

Frequently Asked Questions

What is Proline?
Proline (C₅H₉NO₂) is a organic compound with the IUPAC name (2S)-Pyrrolidine-2-carboxylic acid.
What is the molecular weight of Proline?
Proline has a molar mass of 115.13 g/mol.
What state is Proline at room temperature?
Proline is a solid at room temperature.
Is Proline organic or inorganic?
Proline is classified as an organic compound.
What elements make up Proline?
Proline (C₅H₉NO₂) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O).