Oxidation of Secondary Alcohol to Ketone

R2CHOH + [O] → R2CO + H2O

Aperçu

Secondary alcohols are oxidized to ketones by various oxidizing agents. Unlike primary alcohols, secondary alcohols cannot be over-oxidized because ketones lack the C-H bond needed for further oxidation. The Jones reagent (CrO₃/H₂SO₄) is a standard reagent for this transformation.

Participants

Rôle Substance Coefficient État
Produit Water H₂O 1 (l)

Exemple du quotidien

Acetone (propanone), the simplest ketone and a common nail polish remover solvent, can be made by oxidizing isopropanol.

Importance industrielle

Ketone synthesis is important in pharmaceutical manufacturing, perfume production (muscone, civetone), and in producing industrial solvents.

Propriétés

Type
Organic
Réversible
Non
Énergie
Exothermique
ΔH
-170,0 kJ/mol
Catalyseur
CrO₃ in H₂SO₄ (Jones reagent)

Réactions associées

Epoxidation of Alkenes (mCPBA) Swern Oxidation E2 Elimination (Dehydrohalogenation) Claisen Condensation (Ethyl Acetate) Aldol Condensation of Acetaldehyde Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Catalytic Hydrogenation of Ethylene Dehydration of Ethanol

Frequently Asked Questions

What is the equation for Oxidation of Secondary Alcohol to Ketone?
The balanced equation is: R₂CHOH + [O] → R₂CO + H₂O.
What type of reaction is Oxidation of Secondary Alcohol to Ketone?
Oxidation of Secondary Alcohol to Ketone is a organic reaction.
Is Oxidation of Secondary Alcohol to Ketone exothermic or endothermic?
Oxidation of Secondary Alcohol to Ketone is exothermic (releases energy). The enthalpy change (ΔH) is -170.0 kJ/mol.
What conditions are needed for Oxidation of Secondary Alcohol to Ketone?
This reaction requires a catalyst (CrO₃ in H₂SO₄ (Jones reagent)).