Protein Folding
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단백질 접힘
Definition
The physical process by which a polypeptide chain acquires its functional three-dimensional structure, driven by hydrophobic interactions, hydrogen bonds, and disulfide bridges.
Detailed Explanation
Misfolded proteins can aggregate into insoluble fibrils associated with diseases such as Alzheimer's and Parkinson's. Molecular chaperones assist correct folding in the crowded cellular environment.