Cisplatin

Pt(NH₃)₂Cl₂

IUPAC: cis-Diamminedichloroplatinum(II)

CAS: 15663-27-1

Visão geral

Cisplatin is one of the most effective anticancer drugs, used to treat testicular, ovarian, bladder, and many other cancers. It crosslinks DNA to kill cancer cells.

Composição

Elemento Símbolo Átomos Massa atômica
Hydrogen H 6 1,0080
Nitrogen N 2 14,0070
Chlorine Cl 2 35,4500
Platinum Pt 1 195,0800

Composição elemental

H
Hydrogen ×6
2,0%
N
Nitrogen ×2
9,3%
Cl
Chlorine ×2
23,6%
Pt
Platinum ×1
65,0%

Usos

  • • Cancer chemotherapy
  • • Testicular cancer
  • • Ovarian cancer
  • • Bladder cancer

Curiosidades

  • ✦ Cured Lance Armstrong's testicular cancer; cure rate for testicular cancer is now over 95% with cisplatin

Segurança

  • ⚠ Kidney toxicity
  • ⚠ Nausea
  • ⚠ Hearing loss
  • ⚠ Nerve damage

Structure

SMILES

N.N.Cl[Pt]Cl

Propriedades

Tipo
inorganic
Estado
solid
Massa molar
300,05 g/mol
Densidade
3,7400 g/cm³
Ponto de fusão
270,0 °C
Solubilidade
2.5 g/L at 25°C

Molecular Descriptors

Exact Mass
298,9556
TPSA
2,0 Ų
H-Bond Donors
2
H-Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
5
Complexity
7,0

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(NH₄)₂S₂O₈

Calcium Hydride

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Xenon Difluoride

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Magnesium Silicate

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Hydroxylamine

NH₃O

Diborane

B₂H₆

Frequently Asked Questions

What is Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is a inorganic compound with the IUPAC name cis-Diamminedichloroplatinum(II).
What is the molecular weight of Cisplatin?
Cisplatin has a molar mass of 300.05 g/mol.
What state is Cisplatin at room temperature?
Cisplatin is a solid at room temperature.
Is Cisplatin organic or inorganic?
Cisplatin is classified as an inorganic compound.
What elements make up Cisplatin?
Cisplatin (Pt(NH₃)₂Cl₂) is composed of Hydrogen (H), Nitrogen (N), Chlorine (Cl), Platinum (Pt).