SN2 Reaction (Ethyl Bromide + Hydroxide)
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C2H5Br + OH− → C2H5OH + Br−
Visão geral
Hydroxide ion attacks the carbon bearing bromine in a backside attack, simultaneously displacing bromide. This bimolecular nucleophilic substitution (SN2) proceeds through a single transition state with inversion of stereochemistry (Walden inversion). The rate depends on both nucleophile and substrate concentrations.
Participantes
| Papel | Substância | Coeficiente | Estado |
|---|---|---|---|
| Produto | Ethanol C₂H₅OH | 1 | (l) |
Exemplo do cotidiano
SN2 reactions are fundamental to understanding how drugs interact with enzyme active sites and how biological methylation occurs.
Importância industrial
As reações SN2 são utilizadas na síntese farmacêutica, na produção de etanol a partir de haletos de etilo e na compreensão de processos biológicos de alquilação.
Propriedades
- Tipo
- Organic
- Reversível
- Não
- Energia
- Exotérmico
- ΔH
- -75,0 kJ/mol