Serotonin
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Cite "Serotonin"
Serotonin. (n.d.). In Compound. Retrieved from /fr/compound/serotonin/
"Serotonin." Compound, /fr/compound/serotonin/.
@misc{serotonin, title={Serotonin}, url={/fr/compound/serotonin/}}
IUPAC: 3-(2-Aminoethyl)-1H-indol-5-ol
CAS: 50-67-9
Aperçu
Serotonin is a monoamine neurotransmitter primarily found in the gastrointestinal tract (about 90%), blood platelets, and central nervous system. It regulates mood, sleep, appetite, and digestion. SSRI antidepressants work by increasing serotonin levels in the brain.
Composition
Usages
- • Mood regulation neurotransmitter
- • SSRI drug target (depression treatment)
- • GI motility regulation
- • Platelet aggregation
Le saviez-vous
- ✦ About 90% of the body's serotonin is in the gut, not the brain
- ✦ Derived from tryptophan in a two-step biosynthetic pathway
Sécurité
- ⚠ Serotonin syndrome from drug interactions can be life-threatening
Structure
SMILES
C1=CC2=C(C=C1O)C(=CN2)CCN
Propriétés
- Type
- organic
- État
- solid
- Masse molaire
- 176,22 g/mol
- Densité
- 1,2400 g/cm³
- Point de fusion
- 167,7 °C
- Solubilité
- 20 g/L at 27°C
Molecular Descriptors
- Exact Mass
- 176,0950
- XLogP
- 0,2
- TPSA
- 62,0 Ų
- H-Bond Donors
- 3
- H-Bond Acceptors
- 2
- Rotatable Bonds
- 2
- Heavy Atoms
- 13
- Complexity
- 174,0