Dopamine
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Cite "Dopamine"
Dopamine. (n.d.). In Compound. Retrieved from /ja/compound/dopamine/
"Dopamine." Compound, /ja/compound/dopamine/.
@misc{dopamine, title={Dopamine}, url={/ja/compound/dopamine/}}
IUPAC: 4-(2-Aminoethyl)benzene-1,2-diol
CAS: 51-61-6
概要
Dopamine is a catecholamine neurotransmitter that plays a central role in reward, motivation, and motor control. It is synthesized from the amino acid tyrosine and is the neurotransmitter depleted in Parkinson's disease. The 'dopamine reward system' drives pleasure and addiction.
組成
用途
- • Neurotransmitter (reward, motivation)
- • Parkinson's disease treatment (as L-DOPA)
- • Emergency vasopressor medication
- • Neuroscience research
豆知識
- ✦ Dopamine is responsible for the pleasure you feel when eating chocolate, listening to music, or achieving a goal
安全性
- ⚠ Cannot cross the blood-brain barrier (L-DOPA used instead)
- ⚠ IV dopamine can cause cardiac arrhythmia
Structure
SMILES
C1=CC(=C(C=C1CCN)O)O
特性
- タイプ
- organic
- 状態
- solid
- モル質量
- 153.18 g/mol
- 密度
- 1.2600 g/cm³
- 融点
- 128.0 °C
- 溶解度
- 600 g/L at 21°C
Molecular Descriptors
- Exact Mass
- 153.0790
- XLogP
- -1.0
- TPSA
- 66.5 Ų
- H-Bond Donors
- 3
- H-Bond Acceptors
- 3
- Rotatable Bonds
- 2
- Heavy Atoms
- 11
- Complexity
- 119.0