Oxidation of Primary Alcohol to Aldehyde

RCH2OH + [O] → RCHO + H2O

概要

Primary alcohols are oxidized to aldehydes using mild oxidizing agents like PCC or Dess-Martin periodinane. Stronger oxidants (KMnO₄, CrO₃) would over-oxidize to the carboxylic acid. The carbon oxidation state changes from -1 to +1. Distilling the aldehyde product during reaction prevents over-oxidation.

参加者

役割 物質 係数 状態
生成物 Water H₂O 1 (l)

日常の例

The formation of acetaldehyde from ethanol in the liver is this type of oxidation, responsible for hangover symptoms.

産業上の重要性

アルコールからアルデヒドへの選択的酸化は、香料・フレーバー製造および医薬品中間体の合成に不可欠である。

特性

タイプ
Organic
可逆的
いいえ
エネルギー
発熱性
ΔH
-175.0 kJ/mol
触媒
PCC (pyridinium chlorochromate)

関連する反応

Swern Oxidation Oxidation of Secondary Alcohol to Ketone Claisen Condensation (Ethyl Acetate) Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Catalytic Hydrogenation of Ethylene Condensation Polymerization (Nylon 6,6) Cope Rearrangement Epoxidation of Alkenes (mCPBA)

Frequently Asked Questions

What is the equation for Oxidation of Primary Alcohol to Aldehyde?
The balanced equation is: RCH₂OH + [O] → RCHO + H₂O.
What type of reaction is Oxidation of Primary Alcohol to Aldehyde?
Oxidation of Primary Alcohol to Aldehyde is a organic reaction.
Is Oxidation of Primary Alcohol to Aldehyde exothermic or endothermic?
Oxidation of Primary Alcohol to Aldehyde is exothermic (releases energy). The enthalpy change (ΔH) is -175.0 kJ/mol.
What conditions are needed for Oxidation of Primary Alcohol to Aldehyde?
This reaction requires a catalyst (PCC (pyridinium chlorochromate)).