SN2 Reaction (Ethyl Bromide + Hydroxide)
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C2H5Br + OH− → C2H5OH + Br−
概要
Hydroxide ion attacks the carbon bearing bromine in a backside attack, simultaneously displacing bromide. This bimolecular nucleophilic substitution (SN2) proceeds through a single transition state with inversion of stereochemistry (Walden inversion). The rate depends on both nucleophile and substrate concentrations.
参加者
| 役割 | 物質 | 係数 | 状態 |
|---|---|---|---|
| 生成物 | Ethanol C₂H₅OH | 1 | (l) |
日常の例
SN2 reactions are fundamental to understanding how drugs interact with enzyme active sites and how biological methylation occurs.
産業上の重要性
SN2反応は医薬品合成、ハロゲン化エチルからのエタノール製造、生体内アルキル化過程の理解に使用される。
特性
- タイプ
- Organic
- 可逆的
- いいえ
- エネルギー
- 発熱性
- ΔH
- -75.0 kJ/mol