Dopamine
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Cite "Dopamine"
Dopamine. (n.d.). In Compound. Retrieved from /ru/compound/dopamine/
"Dopamine." Compound, /ru/compound/dopamine/.
@misc{dopamine, title={Dopamine}, url={/ru/compound/dopamine/}}
IUPAC: 4-(2-Aminoethyl)benzene-1,2-diol
CAS: 51-61-6
Обзор
Dopamine is a catecholamine neurotransmitter that plays a central role in reward, motivation, and motor control. It is synthesized from the amino acid tyrosine and is the neurotransmitter depleted in Parkinson's disease. The 'dopamine reward system' drives pleasure and addiction.
Состав
Применение
- • Neurotransmitter (reward, motivation)
- • Parkinson's disease treatment (as L-DOPA)
- • Emergency vasopressor medication
- • Neuroscience research
Интересные факты
- ✦ Dopamine is responsible for the pleasure you feel when eating chocolate, listening to music, or achieving a goal
Безопасность
- ⚠ Cannot cross the blood-brain barrier (L-DOPA used instead)
- ⚠ IV dopamine can cause cardiac arrhythmia
Structure
SMILES
C1=CC(=C(C=C1CCN)O)O
Свойства
- Тип
- organic
- Состояние
- solid
- Молярная масса
- 153,18 g/mol
- Плотность
- 1,2600 g/cm³
- Температура плавления
- 128,0 °C
- Растворимость
- 600 g/L at 21°C
Molecular Descriptors
- Exact Mass
- 153,0790
- XLogP
- -1,0
- TPSA
- 66,5 Ų
- H-Bond Donors
- 3
- H-Bond Acceptors
- 3
- Rotatable Bonds
- 2
- Heavy Atoms
- 11
- Complexity
- 119,0