Protein Folding
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단백질 접힘
定義
疎水性相互作用・水素結合・ジスルフィド架橋によって駆動されるポリペプチド鎖が機能的な3次元構造を獲得する物理的過程。
詳細な説明
誤って折り畳まれたタンパク質はアルツハイマー病やパーキンソン病に関連する不溶性フィブリルに凝集することがある。分子シャペロンは込み合った細胞環境での正確な折り畳みを助ける。