Atorvastatin

C₃₃H₃₅FN₂O₅

IUPAC: Atorvastatin

CAS: 134523-00-5

概要

Atorvastatin (Lipitor) was the best-selling pharmaceutical in history, generating over $125 billion in revenue. It lowers cholesterol by inhibiting HMG-CoA reductase.

組成

元素 記号 原子 原子質量
Hydrogen H 35 1.0080
Carbon C 33 12.0110
Nitrogen N 2 14.0070
Oxygen O 5 15.9990
Fluorine F 1 18.9980

元素組成

H
Hydrogen ×35
6.3%
C
Carbon ×33
71.0%
N
Nitrogen ×2
5.0%
O
Oxygen ×5
14.3%
F
Fluorine ×1
3.4%

用途

  • • Cholesterol reduction
  • • Cardiovascular disease prevention

豆知識

  • ✦ Lipitor became the first drug to exceed $10 billion in annual sales

安全性

  • ⚠ Muscle pain
  • ⚠ Liver enzyme elevation

Structure

SMILES

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

特性

タイプ
organic
状態
solid
モル質量
558.64 g/mol
融点
159.2 °C
溶解度
insoluble

Molecular Descriptors

Exact Mass
558.2530
XLogP
5.0
TPSA
112.0 Ų
H-Bond Donors
4
H-Bond Acceptors
6
Rotatable Bonds
12
Heavy Atoms
41
Complexity
822.0

関連化合物

Caffeine

C₈H₁₀N₄O₂

Coumarin

C₉H₆O₂

Acetone

(CH₃)₂CO

Acrylic Acid

C₃H₄O₂

Cysteine

C₃H₇NO₂S

DDT

C₁₄H₉Cl₅

Alanine

C₃H₇NO₂

Diazepam

C₁₆H₁₃ClN₂O

Dichloromethane

CH₂Cl₂

Butane

C₄H₁₀

Frequently Asked Questions

What is Atorvastatin?
Atorvastatin (C₃₃H₃₅FN₂O₅) is a organic compound with the IUPAC name Atorvastatin.
What is the molecular weight of Atorvastatin?
Atorvastatin has a molar mass of 558.64 g/mol.
What state is Atorvastatin at room temperature?
Atorvastatin is a solid at room temperature.
Is Atorvastatin organic or inorganic?
Atorvastatin is classified as an organic compound.
What elements make up Atorvastatin?
Atorvastatin (C₃₃H₃₅FN₂O₅) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O), Fluorine (F).