Serotonin

C₁₀H₁₂N₂O

IUPAC: 3-(2-Aminoethyl)-1H-indol-5-ol

CAS: 50-67-9

概述

Serotonin is a monoamine neurotransmitter primarily found in the gastrointestinal tract (about 90%), blood platelets, and central nervous system. It regulates mood, sleep, appetite, and digestion. SSRI antidepressants work by increasing serotonin levels in the brain.

组成

元素 符号 原子 原子质量
Hydrogen H 12 1.0080
Carbon C 10 12.0110
Nitrogen N 2 14.0070
Oxygen O 1 15.9990

元素组成

H
Hydrogen ×12
6.9%
C
Carbon ×10
68.2%
N
Nitrogen ×2
15.9%
O
Oxygen ×1
9.1%

用途

  • • Mood regulation neurotransmitter
  • • SSRI drug target (depression treatment)
  • • GI motility regulation
  • • Platelet aggregation

趣味知识

  • ✦ About 90% of the body's serotonin is in the gut, not the brain
  • ✦ Derived from tryptophan in a two-step biosynthetic pathway

安全性

  • ⚠ Serotonin syndrome from drug interactions can be life-threatening

Structure

SMILES

C1=CC2=C(C=C1O)C(=CN2)CCN

属性

类型
organic
状态
solid
摩尔质量
176.22 g/mol
密度
1.2400 g/cm³
熔点
167.7 °C
溶解度
20 g/L at 27°C

Molecular Descriptors

Exact Mass
176.0950
XLogP
0.2
TPSA
62.0 Ų
H-Bond Donors
3
H-Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
13
Complexity
174.0

别名

5-Hydroxytryptamine 5-HT

相关化合物

Caffeine

C₈H₁₀N₄O₂

Coumarin

C₉H₆O₂

Acetone

(CH₃)₂CO

Acrylic Acid

C₃H₄O₂

Cysteine

C₃H₇NO₂S

DDT

C₁₄H₉Cl₅

Alanine

C₃H₇NO₂

Diazepam

C₁₆H₁₃ClN₂O

Dichloromethane

CH₂Cl₂

Butane

C₄H₁₀

Frequently Asked Questions

What is Serotonin?
Serotonin (C₁₀H₁₂N₂O) is a organic compound with the IUPAC name 3-(2-Aminoethyl)-1H-indol-5-ol.
What is the molecular weight of Serotonin?
Serotonin has a molar mass of 176.215 g/mol.
What state is Serotonin at room temperature?
Serotonin is a solid at room temperature.
Is Serotonin organic or inorganic?
Serotonin is classified as an organic compound.
What elements make up Serotonin?
Serotonin (C₁₀H₁₂N₂O) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O).