Tetrahydrofuran

C₄H₈O

IUPAC: Oxolane

CAS: 109-99-9

概述

Tetrahydrofuran (THF) is a cyclic ether widely used as a laboratory and industrial solvent. It is the preferred solvent for Grignard and organolithium reactions and dissolves PVC, making it useful for PVC pipe cement. It can form explosive peroxides on prolonged air exposure.

组成

元素 符号 原子 原子质量
Hydrogen H 8 1.0080
Carbon C 4 12.0110
Oxygen O 1 15.9990

元素组成

H
Hydrogen ×8
11.2%
C
Carbon ×4
66.6%
O
Oxygen ×1
22.2%

用途

  • • Grignard reaction solvent
  • • PVC pipe cement solvent
  • • Polymer chemistry
  • • Pharmaceutical production

趣味知识

  • ✦ The purple color of PVC pipe primer/cement comes from dyes dissolved in THF-based solvent

安全性

  • ⚠ Forms explosive peroxides
  • ⚠ Highly flammable
  • ⚠ CNS depressant
  • ⚠ May cause liver damage

Structure

SMILES

C1CCOC1

属性

类型
organic
状态
liquid
摩尔质量
72.11 g/mol
密度
0.8890 g/cm³
熔点
-108.4 °C
沸点
66.0 °C
溶解度
miscible

Molecular Descriptors

Exact Mass
72.0575
XLogP
0.5
TPSA
9.2 Ų
H-Bond Donors
0
H-Bond Acceptors
1
Rotatable Bonds
0
Heavy Atoms
5
Complexity
22.0

别名

THF

相关化合物

Caffeine

C₈H₁₀N₄O₂

Coumarin

C₉H₆O₂

Acetone

(CH₃)₂CO

Acrylic Acid

C₃H₄O₂

Cysteine

C₃H₇NO₂S

DDT

C₁₄H₉Cl₅

Alanine

C₃H₇NO₂

Diazepam

C₁₆H₁₃ClN₂O

Dichloromethane

CH₂Cl₂

Butane

C₄H₁₀

Frequently Asked Questions

What is Tetrahydrofuran?
Tetrahydrofuran (C₄H₈O) is a organic compound with the IUPAC name Oxolane.
What is the molecular weight of Tetrahydrofuran?
Tetrahydrofuran has a molar mass of 72.107 g/mol.
What state is Tetrahydrofuran at room temperature?
Tetrahydrofuran is a liquid at room temperature.
Is Tetrahydrofuran organic or inorganic?
Tetrahydrofuran is classified as an organic compound.
What elements make up Tetrahydrofuran?
Tetrahydrofuran (C₄H₈O) is composed of Hydrogen (H), Carbon (C), Oxygen (O).