Cis-Trans Isomerization of Retinal
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11-cis-Retinal → all-trans-Retinal
概述
When a photon strikes rhodopsin in rod cells of the retina, it causes the 11-cis-retinal chromophore to isomerize to the all-trans configuration in about 200 femtoseconds. This is one of the fastest known chemical reactions and the fundamental first step in vision. The conformational change triggers a G-protein signaling cascade.
日常示例
Every time you see anything, this photochemical reaction is occurring millions of times per second in the rod and cone cells of your eyes.
工业重要性
理解视黄醛光化学指导了人工视网膜、光遗传学工具以及光敏生物材料的开发。
属性
- 可逆
- 否
- 能量
- 吸热
- 催化剂
- Rhodopsin protein