Oxidation of Secondary Alcohol to Ketone

R2CHOH + [O] → R2CO + H2O

概述

Secondary alcohols are oxidized to ketones by various oxidizing agents. Unlike primary alcohols, secondary alcohols cannot be over-oxidized because ketones lack the C-H bond needed for further oxidation. The Jones reagent (CrO₃/H₂SO₄) is a standard reagent for this transformation.

参与者

角色 物质 系数 状态
产物 Water H₂O 1 (l)

日常示例

Acetone (propanone), the simplest ketone and a common nail polish remover solvent, can be made by oxidizing isopropanol.

工业重要性

仲醇氧化为酮是制备溶剂（如丙酮、甲基乙基酮）和药物中间体的关键工业步骤。

属性

类型
Organic
可逆
否
能量
放热
ΔH
-170.0 kJ/mol
催化剂
CrO₃ in H₂SO₄ (Jones reagent)

相关反应

Swern Oxidation Claisen Condensation (Ethyl Acetate) Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Catalytic Hydrogenation of Ethylene Condensation Polymerization (Nylon 6,6) Cope Rearrangement Oxidation of Primary Alcohol to Aldehyde Epoxidation of Alkenes (mCPBA)

Frequently Asked Questions

What is the equation for Oxidation of Secondary Alcohol to Ketone?
The balanced equation is: R₂CHOH + [O] → R₂CO + H₂O.
What type of reaction is Oxidation of Secondary Alcohol to Ketone?
Oxidation of Secondary Alcohol to Ketone is a organic reaction.
Is Oxidation of Secondary Alcohol to Ketone exothermic or endothermic?
Oxidation of Secondary Alcohol to Ketone is exothermic (releases energy). The enthalpy change (ΔH) is -170.0 kJ/mol.
What conditions are needed for Oxidation of Secondary Alcohol to Ketone?
This reaction requires a catalyst (CrO₃ in H₂SO₄ (Jones reagent)).