SN2 Reaction (Ethyl Bromide + Hydroxide)

C2H5Br + OH− → C2H5OH + Br−

概述

Hydroxide ion attacks the carbon bearing bromine in a backside attack, simultaneously displacing bromide. This bimolecular nucleophilic substitution (SN2) proceeds through a single transition state with inversion of stereochemistry (Walden inversion). The rate depends on both nucleophile and substrate concentrations.

参与者

角色 物质 系数 状态
产物 Ethanol C₂H₅OH 1 (l)

日常示例

SN2 reactions are fundamental to understanding how drugs interact with enzyme active sites and how biological methylation occurs.

工业重要性

SN2反应广泛用于制药合成中手性化合物的制备，精确控制立体化学是药物活性的关键因素。

属性

类型
Organic
可逆
否
能量
放热
ΔH
-75.0 kJ/mol

相关反应

Epoxidation of Alkenes (mCPBA) Swern Oxidation Oxidation of Secondary Alcohol to Ketone E2 Elimination (Dehydrohalogenation) Claisen Condensation (Ethyl Acetate) Aldol Condensation of Acetaldehyde Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Dehydration of Ethanol

Frequently Asked Questions

What is the equation for SN2 Reaction (Ethyl Bromide + Hydroxide)?
The balanced equation is: C₂H₅Br + OH⁻ → C₂H₅OH + Br⁻.
What type of reaction is SN2 Reaction (Ethyl Bromide + Hydroxide)?
SN2 Reaction (Ethyl Bromide + Hydroxide) is a organic reaction.
Is SN2 Reaction (Ethyl Bromide + Hydroxide) exothermic or endothermic?
SN2 Reaction (Ethyl Bromide + Hydroxide) is exothermic (releases energy). The enthalpy change (ΔH) is -75.0 kJ/mol.