Oxidation of Secondary Alcohol to Ketone

R2CHOH + [O] → R2CO + H2O

Tổng quan

Secondary alcohols are oxidized to ketones by various oxidizing agents. Unlike primary alcohols, secondary alcohols cannot be over-oxidized because ketones lack the C-H bond needed for further oxidation. The Jones reagent (CrO₃/H₂SO₄) is a standard reagent for this transformation.

Người tham gia

Vai trò Chất Hệ số Trạng thái
Sản phẩm Water H₂O 1 (l)

Ví dụ thực tế

Acetone (propanone), the simplest ketone and a common nail polish remover solvent, can be made by oxidizing isopropanol.

Tầm quan trọng công nghiệp

Ketone synthesis is important in pharmaceutical manufacturing, perfume production (muscone, civetone), and in producing industrial solvents.

Tính chất

Loại
Organic
Thuận nghịch
Không
Năng lượng
Tỏa nhiệt
ΔH
-170,0 kJ/mol
Chất xúc tác
CrO₃ in H₂SO₄ (Jones reagent)

Phản ứng liên quan

Epoxidation of Alkenes (mCPBA) Swern Oxidation E2 Elimination (Dehydrohalogenation) Claisen Condensation (Ethyl Acetate) Aldol Condensation of Acetaldehyde Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Catalytic Hydrogenation of Ethylene Dehydration of Ethanol

Frequently Asked Questions

What is the equation for Oxidation of Secondary Alcohol to Ketone?
The balanced equation is: R₂CHOH + [O] → R₂CO + H₂O.
What type of reaction is Oxidation of Secondary Alcohol to Ketone?
Oxidation of Secondary Alcohol to Ketone is a organic reaction.
Is Oxidation of Secondary Alcohol to Ketone exothermic or endothermic?
Oxidation of Secondary Alcohol to Ketone is exothermic (releases energy). The enthalpy change (ΔH) is -170.0 kJ/mol.
What conditions are needed for Oxidation of Secondary Alcohol to Ketone?
This reaction requires a catalyst (CrO₃ in H₂SO₄ (Jones reagent)).