SN2 Reaction (Ethyl Bromide + Hydroxide)

C₂H₅Br + OH⁻ → C₂H₅OH + Br⁻

Tổng quan

Hydroxide ion attacks the carbon bearing bromine in a backside attack, simultaneously displacing bromide. This bimolecular nucleophilic substitution (SN2) proceeds through a single transition state with inversion of stereochemistry (Walden inversion). The rate depends on both nucleophile and substrate concentrations.

Người tham gia

Vai trò	Chất	Hệ số	Trạng thái
Sản phẩm	Ethanol C₂H₅OH	1	(l)

Ví dụ thực tế

SN2 reactions are fundamental to understanding how drugs interact with enzyme active sites and how biological methylation occurs.

Tầm quan trọng công nghiệp

SN2 reactions are used in pharmaceutical synthesis, in producing ethanol from ethyl halides, and in understanding biological alkylation processes.

Tính chất

Loại: Organic
Thuận nghịch: Không
Năng lượng: Tỏa nhiệt
ΔH: -75,0 kJ/mol

Phản ứng liên quan

Epoxidation of Alkenes (mCPBA) Swern Oxidation Oxidation of Secondary Alcohol to Ketone E2 Elimination (Dehydrohalogenation) Claisen Condensation (Ethyl Acetate) Aldol Condensation of Acetaldehyde Kolbe Electrolysis Baeyer-Villiger Oxidation Beckmann Rearrangement (Cyclohexanone Oxime) Dehydration of Ethanol

Frequently Asked Questions

What is the equation for SN2 Reaction (Ethyl Bromide + Hydroxide)?

The balanced equation is: C₂H₅Br + OH⁻ → C₂H₅OH + Br⁻.

What type of reaction is SN2 Reaction (Ethyl Bromide + Hydroxide)?

SN2 Reaction (Ethyl Bromide + Hydroxide) is a organic reaction.

Is SN2 Reaction (Ethyl Bromide + Hydroxide) exothermic or endothermic?

SN2 Reaction (Ethyl Bromide + Hydroxide) is exothermic (releases energy). The enthalpy change (ΔH) is -75.0 kJ/mol.