Atorvastatina

C₃₃H₃₅FN₂O₅

IUPAC: Atorvastatin

CAS: 134523-00-5

Descripción general

Atorvastatin (Lipitor) was the best-selling pharmaceutical in history, generating over $125 billion in revenue. It lowers cholesterol by inhibiting HMG-CoA reductase.

Composición

Elemento Símbolo Átomos Masa atómica
Hidrógeno H 35 1,0080
Carbono C 33 12,0110
Nitrógeno N 2 14,0070
Oxígeno O 5 15,9990
Flúor F 1 18,9980

Composición elemental

H
Hidrógeno ×35
6,3%
C
Carbono ×33
71,0%
N
Nitrógeno ×2
5,0%
O
Oxígeno ×5
14,3%
F
Flúor ×1
3,4%

Usos

  • • Cholesterol reduction
  • • Cardiovascular disease prevention

Datos curiosos

  • ✦ Lipitor became the first drug to exceed $10 billion in annual sales

Seguridad

  • ⚠ Muscle pain
  • ⚠ Liver enzyme elevation

Estructura

SMILES

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

Propiedades

Tipo
organic
Estado
solid
Masa molar
558,64 g/mol
Punto de fusión
159,2 °C
Solubilidad
insoluble

Descriptores moleculares

Masa exacta
558,2530
XLogP
5,0
TPSA
112,0 Ų
Donadores de enlace de hidrógeno
4
Aceptores de enlace de hidrógeno
6
Enlaces rotables
12
Átomos pesados
41
Complejidad
822,0

Compuestos relacionados

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C₂H₄Cl₂

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1,4-Dioxano

C₄H₈O₂

1-Butanol

C₄H₁₀O

2-Propanol

C₃H₈O

Acetaldehído

CH₃CHO

Acetamida

C₂H₅NO

Acetato de butilo

C₆H₁₂O₂

Acetato de etilo

C₄H₈O₂

Acetato de vinilo

C₄H₆O₂

Frequently Asked Questions

What is Atorvastatina?
Atorvastatina (C₃₃H₃₅FN₂O₅) is a organic compound with the IUPAC name Atorvastatin.
What is the molecular weight of Atorvastatina?
Atorvastatina has a molar mass of 558.64 g/mol.
What state is Atorvastatina at room temperature?
Atorvastatina is a solid at room temperature.
Is Atorvastatina organic or inorganic?
Atorvastatina is classified as an organic compound.
What elements make up Atorvastatina?
Atorvastatina (C₃₃H₃₅FN₂O₅) is composed of Hidrógeno (H), Carbono (C), Nitrógeno (N), Oxígeno (O), Flúor (F).