Atorvastatin

C₃₃H₃₅FN₂O₅

IUPAC: Atorvastatin

CAS: 134523-00-5

Descripción general

Atorvastatin (Lipitor) was the best-selling pharmaceutical in history, generating over $125 billion in revenue. It lowers cholesterol by inhibiting HMG-CoA reductase.

Composición

Elemento	Símbolo	Átomos	Masa atómica
Hydrogen	H	35	1,0080
Carbon	C	33	12,0110
Nitrogen	N	2	14,0070
Oxygen	O	5	15,9990
Fluorine	F	1	18,9980

Composición elemental

Hydrogen ×35

6,3%

Carbon ×33

71,0%

Nitrogen ×2

5,0%

Oxygen ×5

14,3%

Fluorine ×1

3,4%

Usos

• Cholesterol reduction
• Cardiovascular disease prevention

Datos curiosos

✦ Lipitor became the first drug to exceed $10 billion in annual sales

Seguridad

⚠ Muscle pain
⚠ Liver enzyme elevation

Structure

SMILES

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

Propiedades

Tipo: organic
Estado: solid
Masa molar: 558,64 g/mol
Punto de fusión: 159,2 °C
Solubilidad: insoluble

Molecular Descriptors

Exact Mass: 558,2530
XLogP: 5,0
TPSA: 112,0 Å²
H-Bond Donors: 4
H-Bond Acceptors: 6
Rotatable Bonds: 12
Heavy Atoms: 41
Complexity: 822,0

Compuestos relacionados

Caffeine

C₈H₁₀N₄O₂

Coumarin

C₉H₆O₂

Acetone

(CH₃)₂CO

Acrylic Acid

C₃H₄O₂

Cysteine

C₃H₇NO₂S

DDT

C₁₄H₉Cl₅

Alanine

C₃H₇NO₂

Diazepam

C₁₆H₁₃ClN₂O

Dichloromethane

CH₂Cl₂

Butane

C₄H₁₀

Frequently Asked Questions

What is Atorvastatin?

Atorvastatin (C₃₃H₃₅FN₂O₅) is a organic compound with the IUPAC name Atorvastatin.

What is the molecular weight of Atorvastatin?

Atorvastatin has a molar mass of 558.64 g/mol.

What state is Atorvastatin at room temperature?

Atorvastatin is a solid at room temperature.

Is Atorvastatin organic or inorganic?

Atorvastatin is classified as an organic compound.

What elements make up Atorvastatin?

Atorvastatin (C₃₃H₃₅FN₂O₅) is composed of Hydrogen (H), Carbon (C), Nitrogen (N), Oxygen (O), Fluorine (F).