Protein Folding
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단백질 접힘
Definición
El proceso físico por el cual una cadena polipeptídica adquiere su estructura tridimensional funcional, impulsado por interacciones hidrofóbicas, puentes de hidrógeno y puentes disulfuro.
Explicación detallada
Las proteínas mal plegadas pueden agregarse en fibrillas insolubles asociadas con enfermedades como el Alzheimer y el Parkinson. Las chaperonas moleculares asisten al plegamiento correcto en el abarrotado entorno celular.