Formación de amida (ácido acético + amoniaco)

CH3COOH + NH3 → CH3CONH2 + H2O

Descripción general

Acetic acid reacts with ammonia to first form ammonium acetate, which upon strong heating loses water to form acetamide. The amide bond (C-N) is the same linkage found in proteins (peptide bonds). Direct thermal dehydration is energy-intensive; industrial methods use acyl chlorides or coupling reagents.

Participantes

Rol Sustancia Coeficiente Estado
Reactivo Ácido acético CH₃COOH 1 (l)
Reactivo Amoniaco NH₃ 1 (g)
Producto Agua H₂O 1 (l)

Ejemplo cotidiano

Every protein in your body is held together by amide (peptide) bonds, the same type of bond formed in this reaction.

Importancia industrial

La formación del enlace amida es fundamental para la síntesis de péptidos, la fabricación farmacéutica y la producción de nailon (poliamida).

Preguntas frecuentes

What is the equation for Formación de amida (ácido acético + amoniaco)?
The balanced equation is: CH₃COOH + NH₃ → CH₃CONH₂ + H₂O.
What type of reaction is Formación de amida (ácido acético + amoniaco)?
Formación de amida (ácido acético + amoniaco) is a orgánica reaction.
Is Formación de amida (ácido acético + amoniaco) exothermic or endothermic?
Formación de amida (ácido acético + amoniaco) is exothermic (releases energy). The enthalpy change (ΔH) is -25.0 kJ/mol.
What conditions are needed for Formación de amida (ácido acético + amoniaco)?
This reaction requires a catalyst (Heat).